Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock.
Identifieur interne : 000534 ( Main/Exploration ); précédent : 000533; suivant : 000535Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock.
Auteurs : Olivier Huet [États-Unis] ; Raelene J. Pickering ; Chris Tikellis ; Celine Latouche ; Fenella Long ; Bronwyn Kingwell ; Bryan Dickinson ; Chris J. Chang ; Seth Masters ; Fabienne Mackay ; Mark E. Cooper ; Judy B. De HaanSource :
- Critical care medicine [ 1530-0293 ] ; 2017.
Descripteurs français
- KwdFr :
- Animaux, Antioxydants (usage thérapeutique), Choc septique (anatomopathologie), Choc septique (physiopathologie), Espèces réactives de l'oxygène (métabolisme), Femelle, Glutathione peroxidase (métabolisme), Infections à Klebsiella (physiopathologie), Inflammasomes (physiologie), Klebsiella pneumoniae, Modèles animaux de maladie humaine, Mâle, Peroxyde d'hydrogène (métabolisme), Pneumopathie bactérienne (anatomopathologie), Pneumopathie bactérienne (physiopathologie), Poumon (anatomopathologie), Réaction de polymérisation en chaine en temps réel, Souris, Souris de lignée C57BL, Souris knockout, Technique de Western.
- MESH :
- anatomopathologie : Choc septique, Pneumopathie bactérienne, Poumon.
- métabolisme : Espèces réactives de l'oxygène, Glutathione peroxidase, Peroxyde d'hydrogène.
- physiologie : Inflammasomes.
- physiopathologie : Choc septique, Infections à Klebsiella, Pneumopathie bactérienne.
- usage thérapeutique : Antioxydants.
- Animaux, Femelle, Klebsiella pneumoniae, Modèles animaux de maladie humaine, Mâle, Réaction de polymérisation en chaine en temps réel, Souris, Souris de lignée C57BL, Souris knockout, Technique de Western.
English descriptors
- KwdEn :
- Animals, Antioxidants (therapeutic use), Blotting, Western, Disease Models, Animal, Female, Glutathione Peroxidase (metabolism), Hydrogen Peroxide (metabolism), Inflammasomes (physiology), Klebsiella Infections (physiopathology), Klebsiella pneumoniae, Lung (pathology), Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Pneumonia, Bacterial (pathology), Pneumonia, Bacterial (physiopathology), Reactive Oxygen Species (metabolism), Real-Time Polymerase Chain Reaction, Shock, Septic (pathology), Shock, Septic (physiopathology).
- MESH :
- chemical , metabolism : Glutathione Peroxidase, Hydrogen Peroxide, Reactive Oxygen Species.
- chemical , physiology : Inflammasomes.
- chemical , therapeutic use : Antioxidants.
- pathology : Lung, Pneumonia, Bacterial, Shock, Septic.
- physiopathology : Klebsiella Infections, Pneumonia, Bacterial, Shock, Septic.
- Animals, Blotting, Western, Disease Models, Animal, Female, Klebsiella pneumoniae, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Real-Time Polymerase Chain Reaction.
Abstract
To study the effect of a lack of antioxidant defenses during lethal pneumonia induced by Klebsiella pneumonia, compared to wild-type mice.
DOI: 10.1097/CCM.0000000000002070
PubMed: 27749344
Affiliations:
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Le document en format XML
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Pickering</name></author><author><name sortKey="Tikellis, Chris" sort="Tikellis, Chris" uniqKey="Tikellis C" first="Chris" last="Tikellis">Chris Tikellis</name></author><author><name sortKey="Latouche, Celine" sort="Latouche, Celine" uniqKey="Latouche C" first="Celine" last="Latouche">Celine Latouche</name></author><author><name sortKey="Long, Fenella" sort="Long, Fenella" uniqKey="Long F" first="Fenella" last="Long">Fenella Long</name></author><author><name sortKey="Kingwell, Bronwyn" sort="Kingwell, Bronwyn" uniqKey="Kingwell B" first="Bronwyn" last="Kingwell">Bronwyn Kingwell</name></author><author><name sortKey="Dickinson, Bryan" sort="Dickinson, Bryan" uniqKey="Dickinson B" first="Bryan" last="Dickinson">Bryan Dickinson</name></author><author><name sortKey="Chang, Chris J" sort="Chang, Chris J" uniqKey="Chang C" first="Chris J" last="Chang">Chris J. 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De Haan</name></author></analytic><series><title level="j">Critical care medicine</title><idno type="eISSN">1530-0293</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antioxidants (therapeutic use)</term><term>Blotting, Western</term><term>Disease Models, Animal</term><term>Female</term><term>Glutathione Peroxidase (metabolism)</term><term>Hydrogen Peroxide (metabolism)</term><term>Inflammasomes (physiology)</term><term>Klebsiella Infections (physiopathology)</term><term>Klebsiella pneumoniae</term><term>Lung (pathology)</term><term>Male</term><term>Mice</term><term>Mice, Inbred C57BL</term><term>Mice, Knockout</term><term>Pneumonia, Bacterial (pathology)</term><term>Pneumonia, Bacterial (physiopathology)</term><term>Reactive Oxygen Species (metabolism)</term><term>Real-Time Polymerase Chain Reaction</term><term>Shock, Septic (pathology)</term><term>Shock, Septic (physiopathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antioxydants (usage thérapeutique)</term><term>Choc septique (anatomopathologie)</term><term>Choc septique (physiopathologie)</term><term>Espèces réactives de l'oxygène (métabolisme)</term><term>Femelle</term><term>Glutathione peroxidase (métabolisme)</term><term>Infections à Klebsiella (physiopathologie)</term><term>Inflammasomes (physiologie)</term><term>Klebsiella pneumoniae</term><term>Modèles animaux de maladie humaine</term><term>Mâle</term><term>Peroxyde d'hydrogène (métabolisme)</term><term>Pneumopathie bactérienne (anatomopathologie)</term><term>Pneumopathie bactérienne (physiopathologie)</term><term>Poumon (anatomopathologie)</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Souris</term><term>Souris de lignée C57BL</term><term>Souris knockout</term><term>Technique de Western</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glutathione Peroxidase</term><term>Hydrogen Peroxide</term><term>Reactive Oxygen Species</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Inflammasomes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antioxidants</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Choc septique</term><term>Pneumopathie bactérienne</term><term>Poumon</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Espèces réactives de l'oxygène</term><term>Glutathione peroxidase</term><term>Peroxyde d'hydrogène</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term><term>Pneumonia, Bacterial</term><term>Shock, Septic</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Inflammasomes</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Choc septique</term><term>Infections à Klebsiella</term><term>Pneumopathie bactérienne</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Klebsiella Infections</term><term>Pneumonia, Bacterial</term><term>Shock, Septic</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antioxydants</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Blotting, Western</term><term>Disease Models, Animal</term><term>Female</term><term>Klebsiella pneumoniae</term><term>Male</term><term>Mice</term><term>Mice, Inbred C57BL</term><term>Mice, Knockout</term><term>Real-Time Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Femelle</term><term>Klebsiella pneumoniae</term><term>Modèles animaux de maladie humaine</term><term>Mâle</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Souris</term><term>Souris de lignée C57BL</term><term>Souris knockout</term><term>Technique de Western</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To study the effect of a lack of antioxidant defenses during lethal pneumonia induced by Klebsiella pneumonia, compared to wild-type mice.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><noCountry><name sortKey="Chang, Chris J" sort="Chang, Chris J" uniqKey="Chang C" first="Chris J" last="Chang">Chris J. Chang</name><name sortKey="Cooper, Mark E" sort="Cooper, Mark E" uniqKey="Cooper M" first="Mark E" last="Cooper">Mark E. Cooper</name><name sortKey="De Haan, Judy B" sort="De Haan, Judy B" uniqKey="De Haan J" first="Judy B" last="De Haan">Judy B. De Haan</name><name sortKey="Dickinson, Bryan" sort="Dickinson, Bryan" uniqKey="Dickinson B" first="Bryan" last="Dickinson">Bryan Dickinson</name><name sortKey="Kingwell, Bronwyn" sort="Kingwell, Bronwyn" uniqKey="Kingwell B" first="Bronwyn" last="Kingwell">Bronwyn Kingwell</name><name sortKey="Latouche, Celine" sort="Latouche, Celine" uniqKey="Latouche C" first="Celine" last="Latouche">Celine Latouche</name><name sortKey="Long, Fenella" sort="Long, Fenella" uniqKey="Long F" first="Fenella" last="Long">Fenella Long</name><name sortKey="Mackay, Fabienne" sort="Mackay, Fabienne" uniqKey="Mackay F" first="Fabienne" last="Mackay">Fabienne Mackay</name><name sortKey="Masters, Seth" sort="Masters, Seth" uniqKey="Masters S" first="Seth" last="Masters">Seth Masters</name><name sortKey="Pickering, Raelene J" sort="Pickering, Raelene J" uniqKey="Pickering R" first="Raelene J" last="Pickering">Raelene J. Pickering</name><name sortKey="Tikellis, Chris" sort="Tikellis, Chris" uniqKey="Tikellis C" first="Chris" last="Tikellis">Chris Tikellis</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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